National Standard Code
A03.06
GB/T 15657-2021
Category
Heart-related diseases and syndromes

Traditional Chinese Medicine Definition

The disease known as "Manic Depression Tendency" in Chinese medicine, also referred to as "Manic Syndrome," falls under the category of heart-related diseases. According to the records in "Internal Medicine of Traditional Chinese Medicine," Manic Syndrome is characterized by symptoms such as depression of the mind, apathetic expression, mutism, and incoherent speech. The pathological mechanism primarily involves the stagnation of phlegm and Qi, deficiency of both the heart and spleen, and is attributed to disharmony of the emotions, liver Qi stagnation, and internal blockage of phlegm and dampness.

In clinical practice of traditional Chinese medicine, the core pathogenesis of Manic Syndrome is the stagnation of phlegm and Qi, as well as deficiency of both the heart and spleen. Common precipitating factors include emotional disharmony, irregular diet, and excessive fatigue. During the process of differentiation, it is crucial to distinguish between the syndrome of phlegm and Qi stagnation and the syndrome of deficiency of both the heart and spleen. The syndrome of phlegm and Qi stagnation is characterized by depression of the mind, apathetic expression, mutism, and incoherent speech, with the treatment approach focusing on regulating Qi, resolving depression, and dissolving phlegm to open the orifices. The syndrome of deficiency of both the heart and spleen is characterized by confusion of the mind, reversal of dreams, palpitations, easy to be startled, and a tendency to weep and feel sad, with the treatment approach focusing on strengthening the spleen and nourishing the heart, and invigorating Qi to calm the mind. The overall direction of treatment suggests that attention should be paid to harmonizing the emotions, soothing the liver, and resolving depression, while adjusting the spleen and stomach according to the specific syndrome, and transforming dampness and phlegm. During the process of differential diagnosis and treatment, it is essential to adhere to the holistic concept and principle of differential diagnosis and treatment in traditional Chinese medicine, comprehensively considering the patient's constitution, condition, and living environment, and formulating an individualized treatment plan.

Common Syndrome Types and Key Points of Differentiation

Phlegm-Qi Stagnation Syndrome

Main Manifestations: Depression, apathy, mutism, confusion, incoherent speech

Management Approach: Regulate Qi and Resolve Stagnation, Dissolve Phlegm and Open the Orifices

Deficiency of both heart and spleen

Main Manifestations: Dazed and confused, dreams and reality are reversed, palpitations, easy to be startled, prone to sadness and crying

Management Approach: Strengthen the Spleen and Nourish the Heart, Tonify Qi and Calm the Mind

The above syndrome information is based on traditional Chinese medicine textbooks and clinical standards. Specific differentiation should be completed by a practicing traditional Chinese medicine physician in person.

Physician's Clinical Insights

The physician's insight is that patients with Manic Syndrome often suffer from anxiety and depression, and clinical treatment should pay attention to the balanced regulation of the heart, liver, and spleen organs.

— Wang Zhengxiang Traditional Chinese Medicine Practitioner

Reviewed by: Wang Zhengxiang (Traditional Chinese Medicine Practitioner) | 2026-07-07 | Version 2

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This page is for the popular science of traditional Chinese medicine knowledge and does not constitute medical advice. Specific diagnosis should be completed by a licensed traditional Chinese medicine practitioner in person.

This article has been reviewed by licensed TCM physicians at Hangzhou Kezhentang TCM Clinic. It is for TCM popular science reference only and does not involve specific treatment plan recommendations.

References: Internal Medicine of TCM (13th Five-Year Plan Textbook), Diagnostic and Therapeutic Effectiveness Standards for TCM Diseases and Syndromes (ZY/T001.1-94), Classification and Codes of TCM Diseases and Syndromes (GB/T 15657-2021)

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